Bis(chloromethyl) ketone

Bis(chloromethyl) ketone
Names
	Preferred IUPAC name 1,3-Dichloropropan-2-one
	Other names 1,3-Dichloroacetone; α,α'-Dichloroacetone
Identifiers
CAS Number	534-07-6 ;
3D model (JSmol)	Interactive image;
ChEMBL	ChEMBL1231783;
ChemSpider	21106513;
EC Number	208-585-6;
PubChem CID	10793;
UNII	UFH8559WS5;
UN number	2649
	InChI InChI=1S/C3H4Cl2O/c4-1-3(6)2-5/h1-2H2 Key: SUNMBRGCANLOEG-UHFFFAOYSA-N; InChI=1/C3H4Cl2O/c4-1-3(6)2-5/h1-2H2 Key: SUNMBRGCANLOEG-UHFFFAOYAE;
	SMILES ClCC(=O)CCl;
Properties
Chemical formula	C3H4Cl2O
Molar mass	126.96 g·mol−1
Hazards
	Occupational safety and health (OHS/OSH):
Main hazards	Extremely toxic. Dangerous to the skin and eyes
	GHS labelling:
Pictograms
Signal word	Danger
Hazard statements	H300, H310, H314, H330, H341, H410
Precautionary statements	P201, P202, P260, P262, P264, P270, P271, P273, P280, P281, P284, P301+P310, P301+P330+P331, P302+P350, P303+P361+P353, P304+P340, P305+P351+P338, P308+P313, P310, P320, P321, P322, P330, P361, P363, P391, P403+P233, P405, P501
NFPA 704 (fire diamond)	<imagemap> File:NFPA 704.svg\|80px\|alt=NFPA 704 four-colored diamond poly 150 150 300 300 150 450 0 300 Health 4: Very short exposure could cause death or major residual injury. E.g. VX gas poly 300 0 450 150 300 300 150 150 Flammability 1: Must be pre-heated before ignition can occur. Flash point over 93 °C (200 °F). E.g. canola oil poly 450 150 600 300 450 450 300 300 Instability 0: Normally stable, even under fire exposure conditions, and is not reactive with water. E.g. liquid nitrogen poly 300 300 450 450 300 600 150 450 Special hazards (white): no code desc none </imagemap> 4 1 0
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Bis(chloromethyl) ketone is a chemical substance with formula C
₃H
₄Cl
₂O. It is a solid, and is used in the making of citric acid. Exposures such as contact or inhalation of bis(chloromethyl) ketone can result in irritation or damage to skin, eyes, throat, lungs, liver and kidneys, as well as headaches and fainting.^[1] As both chlorine atoms tend to react at the same time, the compound is primarily useful for synthesis of various ring compounds.^[2]

Legal aspects

Bis(chloromethyl) ketone is a substance which is classified as an extremely hazardous substance in the United States as defined in Section 302 of the U.S. Emergency Planning and Community Right-to-Know Act (42 U.S.C. 11002), and is subject to strict reporting requirements by facilities which produce, store, or use it in significant quantities.^[3]

References

^ Hazardous Substance Fact Sheet from the New Jersey Department of Health and Senior Services
^ DePuy, Charles H.; Pettigrew, Jeremy D. "1,3&x2011;Dichloroacetone". Encyclopedia of Reagents for Organic Synthesis. doi:10.1002/047084289X.rd083.pub2.
^ 40 C.F.R.: Appendix A to Part 355—The List of Extremely Hazardous Substances and Their Threshold Planning Quantities (PDF) (Report) (July 1, 2008 ed.). Government Printing Office. Archived from the original (PDF) on February 25, 2012. Retrieved October 29, 2011.

[1] Hazardous Substance Fact Sheet from the New Jersey Department of Health and Senior Services

[2] DePuy, Charles H.; Pettigrew, Jeremy D. "1,3&x2011;Dichloroacetone". Encyclopedia of Reagents for Organic Synthesis. doi:10.1002/047084289X.rd083.pub2.

[gov-right-know-3] 40 C.F.R.: Appendix A to Part 355—The List of Extremely Hazardous Substances and Their Threshold Planning Quantities (PDF) (Report) (July 1, 2008 ed.). Government Printing Office. Archived from the original (PDF) on February 25, 2012. Retrieved October 29, 2011.

[1]

[2]

[3]

Legal aspects

See also

References