File:Ijms-23-00635-g001-550.webp
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Summary
| Description |
English: Replication of the bacteriophage ϕ29 genome.
Per the authors: "(A) The 3′-terminal region of bacteriophage ϕ29 genome. (B) The p6 protein (red) destabilizes the ends of the DNA, making replication possible. The initiation of replication of bacteriophage ϕ29 occurs through the terminal protein p3 (green) which is covalently bound to the 5′ end. DNA polymerase (orange) in complex with p3 protein and dAMP pairs the first nucleotide with the penultimate T from the template. A sliding-back mechanism then occurs, which results in the entire complex moving to the +1 position of the newly synthesized strand, allowing re-matching at the penultimate template site. The ssDNA is covered by p5 SSB (blue). Schemes follow the same formatting." |
| Date | |
| Source | https://www.mdpi.com/1422-0067/23/2/635/htm |
| Author | Joanna Morcinek-Orłowska, Karolina Zdrojewska, and Alicja Węgrzyn |
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 00:03, 3 November 2022 | | 2,163 × 2,026 (450 KB) | wikimediacommons>TheNthEditor | Higher resolution (from same article) |
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