LANCL1

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LanC like 1 is a protein that in humans is encoded by the LANCL1 gene.

Function

This gene encodes a loosely associated peripheral membrane protein related to the LanC family of bacterial membrane-associated proteins involved in the biosynthesis of antimicrobial peptides. This protein may play a role as a peptide-modifying enzyme component in eukaryotic cells. Previously considered a member of the G-protein-coupled receptor superfamily, this protein is now in the LanC family. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Further reading

• Zhang W, Wang L, Liu Y, Xu J, Zhu G, Cang H, Li X, Bartlam M, Hensley K, Li G, Rao Z, Zhang XC (2009). "Structure of human lanthionine synthetase C-like protein 1 and its interaction with Eps8 and glutathione". Genes Dev. 23 (12): 1387–92. doi:10.1101/gad.1789209. PMC 2701572. PMID 19528316.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.