PPIL3
An Error has occurred retrieving Wikidata item for infobox Peptidyl-prolyl cis-trans isomerase-like 3 is an enzyme that in humans is encoded by the PPIL3 gene.[1][2]
Function
This gene encodes a member of the cyclophilin family. Cyclophilins catalyze the cis-trans isomerization of peptidylprolyl imide bonds in oligopeptides. They have been proposed to act either as catalysts or as molecular chaperones in protein-folding events. Transcript variants derived from alternative splicing and/or alternative polyadenylation exist; some of these variants encode different isoforms.[2]
References
- ^ Zhou Z, Ying K, Dai J, Tang R, Wang W, Huang Y, Zhao W, Xie Y, Mao Y (Jul 2001). "Molecular cloning and characterization of a novel peptidylprolyl isomerase (cyclophilin)-like gene (PPIL3) from human fetal brain". Cytogenetics and Cell Genetics. 92 (3–4): 231–6. doi:10.1159/000056909. PMID 11435694. S2CID 713529.
- ^ 2.0 2.1 "Entrez Gene: PPIL3 peptidylprolyl isomerase (cyclophilin)-like 3".
Further reading
- Jurica MS, Licklider LJ, Gygi SR, Grigorieff N, Moore MJ (Apr 2002). "Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis". RNA. 8 (4): 426–39. doi:10.1017/S1355838202021088. PMC 1370266. PMID 11991638.
- Huang LL, Zhao XM, Huang CQ, Yu L, Xia ZX (Mar 2005). "Structure of recombinant human cyclophilin J, a novel member of the cyclophilin family". Acta Crystallographica Section D. 61 (Pt 3): 316–21. doi:10.1107/S0907444904033189. PMID 15735342.
- Qi ZY, Hui GZ, Li Y, Zhou ZX, Gu SH, Ying K, Xie Y (May 2005). "cDNA microarray in isolation of novel differentially expressed genes related to human glioma and clone of a novel full-length gene". Chinese Medical Journal. 118 (10): 799–805. PMID 15989758.
- Hu H, Huang CQ, Liu HL, Han Y, Yu L, Bi RC (Feb 2005). "Crystallization and preliminary X-ray crystallographic studies of human cyclophilin J". Acta Crystallographica Section F. 61 (Pt 2): 216–8. doi:10.1107/S1744309105000643. PMC 1952245. PMID 16510998.