STK33

An Error has occurred retrieving Wikidata item for infobox Serine/threonine kinase 33 is a protein that in humans is encoded by the STK33 gene.

STK33 was identified as a synthetic lethal gene in KRAS-dependent cell lines.^[1]

STK33 has been considered as a target for reversible male contraceptives and the inhibitor CDD-2807 has been tested successfully in mice.^[2]

References

^ Spoonamore J, Weïwer M, Wei J, Guichard B, Ross NT, Masson K, et al. (2010). "Screen for Inhibitors of STK33 Kinase Activity". Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US). PMID 23658944.
^ "Drug causes reversible male contraception in mice". 10 June 2024.

STK33+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

Lua error in mw.title.lua at line 346: bad argument #2 to 'title.new' (unrecognized namespace name 'Portal').

This membrane protein–related article is a stub. You can help Wikipedia by expanding it.

v t e Enzymes
Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Diffusion-limited enzyme Cofactor Enzyme catalysis
Regulation	Allosteric regulation Cooperativity Enzyme inhibitor Enzyme activator
Classification	EC number Enzyme superfamily Enzyme family List of enzymes
Kinetics	Enzyme kinetics Eadie–Hofstee diagram Hanes–Woolf plot Lineweaver–Burk plot Michaelis–Menten kinetics
Types	EC1 Oxidoreductases (list) EC2 Transferases (list) EC3 Hydrolases (list) EC4 Lyases (list) EC5 Isomerases (list) EC6 Ligases (list) EC7 Translocases (list)