TRIM38

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Tripartite motif containing 38 is a protein that in humans is encoded by the TRIM38 gene.

Function

This gene encodes a member of the tripartite motif (TRIM) family. The encoded protein contains a RING-type zinc finger, B box-type zinc finger and SPRY domain. The function of this protein has not been identified. A pseudogene of this gene is located on the long arm of chromosome 4. [provided by RefSeq, Jul 2012].

Further reading

• Liu X, Lei X, Zhou Z, Sun Z, Xue Q, Wang J, Hung T (February 2011). "Enterovirus 71 induces degradation of TRIM38, a potential E3 ubiquitin ligase". Virol. J. 8: 61. doi:10.1186/1743-422X-8-61. PMC 3048563. PMID 21306652.
• Liu XL, Lei XB, Wang JW, Hong T (February 2011). "[Identification A novel protein TRIM38 that activate NF-kappaB signaling pathways]". Zhonghua Shi Yan He Lin Chuang Bing du Xue Za Zhi (in 中文). 25 (1): 60–2. PMID 21789858.
• Xue Q, Zhou Z, Lei X, Liu X, He B, Wang J, Hung T (2012). "TRIM38 negatively regulates TLR3-mediated IFN-β signaling by targeting TRIF for degradation". PLOS ONE. 7 (10): e46825. Bibcode:2012PLoSO...746825X. doi:10.1371/journal.pone.0046825. PMC 3466175. PMID 23056470.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.